The costs of NEC are substantial worldwide. In 2016 in the United States, Johnson et al estimated costs of medical NEC at $43-74,000 and for surgical NEC (30% of cases) at $138-220,000, with the cost of short bowel syndrome over 5 years costing $1.5million per patient.
In the UK, the estimated costs are lower: surgical NEC is £54-71,000 per patient, and medical NEC is £21-37,000 (Renfrew et al). In 2013 575 cases of surgical NEC cost about £33m (ONS 2013). The costs of sepsis are lower but significant. It is possible to assign costs of mortality and disability based on lost QALYs.
Based on the meta-analysis reductions in NEC, mortality and sepsis, we estimate that if every premature baby born in the UK NHS at less than 34 weeks was given Labinic Drops once they had started milk feeds, and that Labinic was continued until 37 weeks corrected gestation, then the NHS could save £20 million each year including the cost of the Labinic Drops.
None of this includes the suffering and distress caused by these potentially modifiable conditions.
Click on the link to download a Word version of our Guidelines for Labinic Use. You can use and amend this freely.
For use with oral syringe dosing in millitres (recommended for in-hospital use)
For use with inbuilt dropper (recommended for community use)
Click on the link to download a Word version of our Parent Information Leaflet. You can use and amend this freely. Labinic Parent Information Leaflet
Labinic probiotic drops can be stored at room temperature, provided this does not exceed 25 degrees C for prolonged periods (a few hours at 30 degrees C causes no degradation). Do not store below 4 degrees C. Labinic has a long shelf life and probiotic counts are well maintained.
Should I give Labinic if a baby is not receiving milk?
ANSWER: No, we do not recommend this. We recommend that the baby, regardless of age and size, is receiving and tolerating 0.5-1.0ml milk before Labinic is added. In line with Unicef Baby Friendly recommendations, we strongly advocate the use of breastmilk.
What is the red or white plastic band on the bottle neck?
ANSWER: This is an anti-tamper marker that is placed during bottling. It is not a seal. It does not matter if it is split for example.
Sometimes there is a brown deposit in the dropper or the lid?
ANSWER: This is normal and is harmless. It can simply be wiped away with a sterile gauze.
The printed expiry date / batch number on the bottle is faded by spillage of the oily probiotic?
ANSWER: It is important to store Labinic upright, and after swirling it to mix, please wait a minute for the contents to settle. Any oil on the bottle neck or lid should be wiped by a sterile gauze to reduce mess and spillage. We can always confirm the batch number/expiry date of Labinic supplied.
If you wish to report an SI or AE involving Labinic Drops, then please email anonymised clinical details, along with your name and organisation to Report. We undertake to share written anonymised reports with our customers to promote safety and learning.
We work with a number of partners to ensure a reliable supply of Labinic Drops internationally
Distribution of Labinic Drops in the UK is currently directly managed by Biofloratech Ltd
Labinic Drops are available from our distribution partner Medsurge in Australia and New Zealand.
Labinic Drops are available from our distribution partner Safeline in Southern Africa.
Labinic Drops are available from our distribution partner Miller and Miller.
Labinic drops can be ordered directly from Biofloratech. We welcome enquiries from distributors looking to fulfil orders or develop new marketplaces.
Different brands can be very different. Probiotics may be in liquid or powder form, and can contain different types of bacteria, as well as different amounts. Labinic is designed for babies, who normally have Bifidobacteria as the main bacteria in the healthy gut, along with Lactobacillus. The amount of bacteria given daily is also important, as a couple of billion of probiotic bacteria are needed to be able to compete with other, potentially harmful bacteria (like E. Coli which causes food poisoning), or fungi (like Candida which causes thrush). It is also important to be reassured that you are not giving your child other substances, such as animal products, sweeteners, preservatives etc
It is believed that giving ‘healthy’ live bacteria helps to support the normal gut function in babies and young children, which is why Labinic is sometimes used in hospitals. These ‘healthy’ live bacteria are called probiotics (see above for terminology). In the stool of a healthy newborn infant, we would normally find high levels of these types of bacteria. Probiotics can be a natural way to maintain the healthy bacteria to promote a normal digestive tract.
Labinic Drops are therefore used to maintain normal digestive health, rather than to "treat" illnesses. As they are not a treatment, they are not classed as a drug or pharmaceutical
Labinic has been specially designed for babies and children. Using all the latest evidence, and working with paediatricians, neonatologists and PhD scientists, we have blended 3 important bacteria, in a ratio where the bifidobacteria are in higher numbers just like in the healthy human infant gut.
Not yet, but you can order Labinic Drops directly from us
This is perfectly normal, and usually means that the Labinic needs to be mixed a bit more thoroughly. The deposits are entirely harmless. After more mixing, if the deposit is still present, simply wipe it away with a sterile gauze. The performance of the Labinic will not be affected.
We will normally respond to your email within 1 working day
Our office is open: 09:30 to 16:30, Monday to Thursday 09:30 to 15:00, Friday Phone (within UK) 01932 506 181 Phone (overseas) +44 1932 506 181